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While no single direct mechanism has been definitively established, fatigue likely results from multiple factors including substantial caloric restriction, gastrointestinal side effects, dehydration, and metabolic adaptation during weight loss

According to the Missouri Poison Center, signs of a semaglutide overdose include: Feeling lightheaded or dizzy Feeling shaky or jittery Sweating, chills and clamminess Irritability or impatience Headache Weakness Fatigue Nausea and/or vomiting Seizures Confusion Passing out If you think you have overdosed on a weight loss drug, Brown said the best thing to do is call your local poison control center or the national hotline at 800-222-1222

The article explains that the unit measurement in semaglutide prescriptions refers to insulin units, a historical convention carried over from other injectable therapy

Stay hydrated, eat smaller frequent meals, and consider soluble fiber supplements to stabilize intestinal transit and reduce loose stools